Bruker S2 PICOFOX
Fast TXRF Multi-Element Trace Analysis
The S2 PICOFOX, manufactured by Bruker, is the world’s first portable benchtop spectrometer for fast quantitative and semi-quantitative multi-element microanalysis of liquids, suspensions, solids and contaminations using TXRF (Total Reflection X-ray Fluorescence Spectroscopy).
The S2 PICOFOX is highly sensitive and ideal for trace element analysis, with detection limits in the ppb and ppm range. The system is particularly suited to working with very small sample quantities, liquids with high matrix content and research involving frequently changing sample types.
No cooling medium is required, so the analyser can be used not only in the laboratory but also for on-site analysis in the field.
- Simultaneous multi-element trace analysis inc. halogenides
- Analyse small sample amounts in the nanogram or microgram range
- Simple quantification using an internal standard
- Extremely flexible – analyse a wide variety of sample types
- Use in the lab or on-site in the field
- No matrix or memory effects
- Low running costs – no consumables or maintenance
- Alternative to ICP-MS – Easier sample preparation and shorter sampling time
TXRF Application Examples
The S2 PICOFOX is extremely flexible, so if your application area is not mentioned here, please get in touch!
Materials such as nanoparticles are used in the production of industrial and consumer products. Ongoing product development accompanied by increasing concerns about the impact on human health and the environment has lead to a growing demand for versatile analytical technologies. In this example, the S2 PICOFOX was used to analyse element ratios in CdSe nanoparticles coated with ZnS.
Pharmaceutical Authenticity Testing
Characterisation of brand drugs and their generics is an essential task in pharmaceutical analysis. Alternative methods such as AAS and ICP-OES are restricted by sample quantity, sample digestion and matrix-related difficulties. TXRF can analyse samples in the microgram range. With internal standardisation, no standards for external calibration are required.
- Trace elements in biological matrices and their impact in clinical chemistry – read the lab report…
- Trace element analysis in blood samples – read the lab report…
- Other biochemical and clinical applications – including trace metals in cell and protein suspensions, and control of dietary supplements and phytoforensics – read the flyer…
Quality Control of Liquid Nutrients and Milk Powder
Take quantitative measurements of macro- and micro- nutrients. Liquid samples can be analysed directly, and powders need only be suspended in a detergent. Detection limits for micro-nutrients in milk and liquid nutritional products are below 300 ppb.
Other Food Applications
- Rapid screening for nutrition-relevant elements in fish – read the lab report…
- Trace element analysis of plant material – read the lab report…
- Detection of toxic elements
- Control of essential macro and trace elements for nutrition and fertilisation control of agricultural plants
- Pesticide and adulterate detection
- Mercury in tap water and orange juice – read the lab report…
- Forensic distance determination after firearm use – read the lab report…
- Other forensics applications – including characterisation of glass fragments – read the flyer…
Mercury in Glass
The use of mercury is essential in the lighting industry, although it is a hazardous element. In production and recycling, it is vital to control mercury levels. Due to its high volatility at room temperature, trace analysis of mercury can be complicated. Common methods such as Cold Vapor Atomic Absorption Spectroscopy (CV AAS) are time consuming and cost intensive. TXRF sample preparation is much faster, simpler and does not require acids. The technique also used internal cailbration, so no solutions for external calibration need to be prepared.
- Qualitative and quantitative analysis of filter samples – read the lab report…
- Toxic elements in fresh water – read the lab report…
- Heavy metals in sewage – read the lab report…
- 20 times increased sensitivity for water analysis with the High Efficiency Module – read the lab report…
- Using Tungsten excitation when analysing environmental samples – read the lab report…