Biological AFM Webinar: Virus Binding Sites

Join Bruker for a biological AFM webinar on Wednesday 8th March 2017 about high resolution imaging and nanomechanical mapping of virus binding sites to animal cells.

Blue Scientific is the official distributor of Bruker AFM in the Nordic region (Sweden, Denmark, Iceland, Finland and Norway). If you have any questions please get in touch:

Watch a recording

 Download the slides

AFM instruments

Contact us on +44 (0)1223 422 269 or info@blue-scientific.com


  

High Resolution Imaging and Nanomechanical Mapping of Virus Binding Sites to Animal Cells

High-force sensitivity and high spatial resolution are important when quantifying and mapping the molecular interactions of biological samples.

Force-distance (FD) curve-based atomic force microscopy is a useful technique for simultaneously contouring the surface and mapping the biophysical properties of biological samples at the nanoscale.

The webinar will cover:

  • How advanced FD-based technology and chemically functionalised tips can be used to study the localisation and interactions of chemical and biological sites on single native proteins and living cells at high resolution.
  • Using atomic force and confocal microscopy to image the surface receptor landscape of cells.
  • How to map virus binding events within the first millisecond of contact with the cell, at high resolution (<50 nm).
  • Theoretical approaches to contouring the free-energy landscape of early binding events, between an engineered virus and cell surface receptors.
AFM and confocal microscopy

True correlation of AFM and optical data

Capabilities of FD-Based AFM

The key capabilities of this biochemically sensitive imaging technique are a powerful complement to other AFM modes for quantitative, high resolution bio-imaging.

  • Quantitative mapping
  • Resolution of a few nanometers
  • True correlation with topography

Speakers

  • Prof. Dr. David Alsteens – Head of NanoBioPhysics group at Université Catholique de Louvain, Belgium
  • Dr. Andra Dumitru – Postdoctoral Fellow, David Alsteens’ group at Université Catholique de Louvain, Belgium

Register

 

The date of the live webinar has now passed. You can watch a recording and download the slides. If you have any questions, please get in touch.

Bruker BioScope Resolve biological AFM

BioScope Resolve

The Bruker BioScope Resolve is an AFM for biological applications, with unmatched features:

  • Highest resolution imaging
  • Most complete biomechanics capabilities
  • Fastest scanning of any bioAFM available

It’s designed for integration with inverted optical light and confocal microscopes. Study a whole range of biological samples, from cells and tissues to molecular and protein structures. You can even combine AFM biomechanics data with real-time confocal and fluorescence microscopy.

Blue Scientific is the official distributor of Bruker AFM in Sweden, Denmark, Iceland, Finland and Norway. If you have any questions please get in touch:

Watch a recording

 Download the slides

 BioScope Resolve

Contact us on +44 (0)1223 422 269 or info@blue-scientific.com